Search on: KETOL-ACID REDUCTOISOMERASE 
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Descriptor English:   Ketol-Acid Reductoisomerase 
Descriptor Spanish:   Cetoácido Reductoisomerasa 
Descriptor Portuguese:   Cetol-Ácido Redutoisomerase 
Tree Number:   D08.811.682.047.524
Definition English:   An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of VALINE; LEUCINE; ISOLEUCINE; pentothenate and COENZYME A. This enzyme was formerly classified as EC 1.1.1.89. 
History Note English:   2006(1980); use VALERATES 1970-1979 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   50599 
Unique Identifier:   D050540 

Occurrence in VHL:
 

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